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APS have been extensively investigated as an immunostimulant and anti-aging, anti-diabetic, anti-tumor, and antiviral agent (Zheng et al., 2020)

A promising herbal compound is luteolin, which improves nerve functions in DN through its antioxidant and neuroprotective effects

Chiral HPLC or Marfey analysis may be warranted to confirm correct D-Trp and D-Phe stereochemistry, as racemization during synthesis can produce less active or inactive diastereomers