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doi: 10.1038/nm.2628 92 SutherlandTELoganNRckerlDHumblesAAAllanSMPapayannopoulosVet al

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245,246 In a randomized controlled trial involving patients with essential hypertension, specific SLC22A12 single nucleotide polymorphisms (SNPs), such as rs11602903, were associated with higher body mass index (BMI), larger waist circumference, higher HDL cholesterol levels, and the presence of metabolic syndrome in individuals of European descent