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Q: I have suffered from diarrhea since starting semaglutide 2.5 months back
Most experts say up to 500 mg per day for a couple of months is generally well tolerated.
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However, the subcutaneous administration of exendin-4 over the last hour reversed this effect, whereas exendin-4 activated AMPK in animals re-fed for two hours when AMPK activity was markedly inhibited
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