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& Hebenstreit, G

Ther Adv Musculoskelet Dis

It often builds slowly, and the cosmetic signs tend to show up alongside subtler systemic symptoms that are easy to dismiss

That decline correlates with reduced wound healing speed, collagen production, and tissue repair capacity

Holst Lange pointed to the additive contribution of cagrilintide as evidence that the amylin mechanism delivers meaningful benefit beyond GLP-1 monotherapy, and noted that higher-dose CagriSema development is ongoing