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Dose adjustment is required in moderate-to-severe renal impairment and in moderate hepatic impairment, and the medication is not recommended in severe hepatic impairment or end-stage renal disease
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Additionally, gene ontology analysis detected accumulation of transcripts related to the three steps of protein synthesis (initiation, elongation, termination) in Gclc fl/fl MZB compared to Gclc fl/fl FoB (Supplementary Fig
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