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278 These pathways lead to granzyme release, ROS production, 279 and the activation of transcription factors, including STAT3, 280 NF-B, activator protein 1 (AP-1), 281 and cAMP-responsive element-binding protein (CREB), 277 which further contributes to the expression of pro-inflammatory cytokines, co-stimulatory molecules, and complement components
Next, we will summarize some promising medicine monomers that activate the GSH system based on the categories of natural medicines, including flavonoids, terpenoids, phenolic acids, quinones, and alkaloids (Table 2, Supplementary Table S2)
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J Int Soc Sports Nutr 17, 49 (2020)
