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Effective contraception includes oral (the pill) and non-oral (the implant, coil or condoms) forms of contraception
GLP-1 drugs may help reduce liver fat and inflammation, potentially slowing disease progression
Excluding patients with a baseline BMI of 35 or higher (overweight and class 1 obesity), rates declined to 8.8% and 12.1% in the low- and high-dose groups, respectively, compared with 4.8% for placebo
Many people unintentionally eat far less protein, fewer vitamins, and fewer minerals sometimes without realizing it
TRIUMPH-4 (Completed December 2025) Primary Endpoints: Weight loss (28.7% achieved) Knee osteoarthritis pain reduction (75.8% improvement) Secondary/Exploratory Endpoints (Liver): Liver enzymes (ALT, AST, GGT) Possibly liver imaging (ultrasound or MRI) in subset Not liver biopsies Expected Publication: 2026 (full results) What We'll Learn: Do liver enzymes normalize with 28.7% weight loss in larger population
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