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We examined cis-trans stereoisomers of ESA and found that isomerization at position 9 (eleostearic acid) or at both 9 and 13 (catalpic acid) retained cell death activity while isomerization at position 13 alone (punicic acid) led to a ~4-fold reduction in potency (Fig
Health experts do not yet know whether these injectable diabetes drugs can cause tumors in humans, but it is important to understand the risk
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Potential benefits include reduced steroid dependence, fewer hospitalizations, and improved durability of advanced therapy
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