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Complacency is the root of dosing errors
The current adult weight-reduction label allows 7.2 mg after at least four weeks at 2.4 mg when additional loss is clinically indicated, and STEP UP measured more weight loss at 7.2 mg than at 2.4 mg. Side effects rise along the same curve
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Bcl-2 is posited as an anti-apoptotic protein that apparently inhibits cell death, while Bax is suggested to be a pro-apoptotic protein that promotes cell death
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