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Fatigue rises, your workouts suffer, and the scale stalls because your body is in preservation mode

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For the early titration phase, consider reconstituting with a smaller amount of water

For patients controlled on LANTUS (insulin glargine, 100 units/mL), expect that a higher daily dose of TOUJEO will be needed to maintain the same level of glycemic control [see Clinical Pharmacology (12.2) and Clinical Studies (14.1)]

Dedicated factorial trials would clarify whether these complementary pathways produce additive, supra-additive, or attenuated effects on hard outcomes