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Importantly, at study completion, 5A-1MQ-treated mice had a lower fat mass than the obese WD controls and their vehicle-treated counterparts and were not significantly different (with FDR correction) from the LD control mice (Fig

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Corticosteroids suppress inflammation through glucocorticoid receptor activation but carry metabolic consequences including insulin resistance, bone density reduction, and hypothalamic-pituitary-adrenal (HPA) axis suppression

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Yi L, Maier AB, Tao R, et al