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GHKCu indirectly supports angiogenesis by enhancing extracellular matrix stability, regulating metalloproteinases, and maintaining endothelial cell viability, creating an environment conducive to vascular growth (16)

One of the latest systematic reviews on the topic covered a total of 4 trials and reported significant improvement in the condition, assessed according to a 72-point scale called Psoriasis Area and Severity Index (PASI)

Excessive intake has also been reported to lead to acid reflux, although scientific evidence does not support this ( If youre experiencing digestive problems as a result of taking too much vitamin C, you can simply cut back your supplement dose or avoid vitamin C supplements altogether ( Summary Ingesting more than 2,000 mg of vitamin C per day may lead to gastrointestinal upset, including symptoms like diarrhea and nausea

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doi: 10.1016/j.cmet.2019.03.002 61 GrunddalKVJensenEPrskovCAndersenDBWindelvJAPoulsenSSet al