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In hereditary or acquired metabolic defects, an initial intravenous bolus of 50 mg/kg may be administered over two to three minutes, followed by maintenance doses of 50 mg/kg every six hours or continuous infusion to achieve a total daily exposure of up to 300 mg/kg in critical illness

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Patients on chronic total parenteral nutrition (TPN) often receive a formulation of vitamins similar to this on a continuous basis

Family 2 Incretin peptides (appetite and insulin pathways): Semaglutide is a single GLP-1 receptor agonist