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It is best consumed fresh or within 24 hours if stored in a clean, sealed container to maintain its effectiveness and freshness
Effects beyond 68 weeks are simply unstudied
By suppressing caspase activation and modifying Bcl-2 family proteins, melatonin also promotes cellular viability
Elevated MOTS-c levels in senescent cells, which are exposed to these peptides, increased mitochondrial respiration and some senescence-associated secretory phenotypes (SASP) in the former, suggesting that mitochondria-secreted peptides exert a therapeutic effect by targeting mitochondrial energy and SASP production in senescent cells 50
IF images were acquired using a Leica TCS-SP8 confocal microscope
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