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pyroglutamic (5-oxoproline) acidosis pyroglutamic (5-oxoproline) acidosis pathophysiology pathogenesis of pyroglutamic acidosis The primary driver may be cysteine deficiency : Cysteine deficiency causes glutamylcysteine to be shunted into 5-oxoproline

Our study provides strong evidences, elucidating that the induction of ferroptosis resistance as an effective strategy to promote the survival of transplanted fat grafts

We conclude that physiological levels of reduced oxygen species are not potent oxidants of typical protein thiols

We focus on the potential role of the amino acid histidine and its interaction with the mineral copper, both to catalyze certain essential reactions and to facilitate the misfolding of amyloidogenic proteins triggered by contact with anionic phospholipids, particularly cardiolipin, and especially in the outer mitochondrial membrane of deuterium-damaged mitochondria

Pastore S, Mariani V, Gubineli E, Raskovic D, Mariani S, et al