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explored the feasibility of ADCs as targeted therapies associated with senolytics
Bulletin of Experimental Biology and Medicine, 164 , 140-143
Mechanism of Action: 2 adrenoreceptor agonist Peripheral : 2 agonists can directly cause arterial vasoconstriction , which can cause an initial phase of hypertension , before centrally mediated effects predominate, resulting in reduced sympathetic outflow from the CNS, which results in both bradycardia and hypotension (Malayala et al, 2022
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