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Unknown Pharmacokinetics We dont fully understand how these medications behave in the body at micro-doses, including their absorption, distribution, and elimination patterns

Solmaz V, Tekatas A, Erdoan MA, Erba O

For example: If your prescribed weekly dose is 0.25mg, a 5mg supply could theoretically provide 20 individual doses (5mg / 0.25mg per dose = 20 doses)

The SURMOUNT-1 trial found participants lost up to 22.5% of their body weight over 72 weeks, one of the most impressive results to date

This is because GLP-1 medications slow gastric emptying, which is part of how they work, and the gut takes time to adapt. Staying hydrated (two to two-and-a-half litres across the day) and keeping moving makes a genuine difference here