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Adverse Reactions Nausea, vomiting, abdominal cramps, diarrhea, and a "fishy" body odor can occur with doses of about 3 g/day

Contact your GP or diabetes care team if you experience: Persistent or worsening rash that does not improve with basic skincare measures Widespread itching (pruritus) that interferes with daily activities or sleep Skin changes affecting mucous membranes (mouth, eyes, or genital areas) Symptoms that develop or worsen despite stopping potential irritants Seek urgent same-day assessment (call NHS 111, visit urgent care, or attend A&E) if you develop: New skin lesions, widespread blistering, or peeling , particularly if accompanied by fever or other systemic symptoms Mucosal involvement with blistering or ulceration Seek immediate medical attention (call 999 or attend A&E) if you develop signs of a severe allergic reaction (anaphylaxis) , including: Angioedema : swelling of the face, lips, tongue, or throat, which may cause difficulty breathing or swallowing Difficulty breathing, wheezing, or chest tightness Rapid onset of widespread urticaria (hives) with systemic symptoms Dizziness, fainting, or rapid heartbeat accompanying skin symptoms These symptoms, though rare, represent medical emergencies requiring immediate intervention

This mechanism of action has shown promising results in improving heart health in individuals with diabetes

In the SURMOUNT-1 trial, patients taking the highest dose achieved up to 22.5% average body weight reduction over 72 weeks