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Body composition measurements, grip strength, and functional capacity are more informative than weight alone
Our previous work showed that CDKN2A expression is elevated in excitotoxicity-damaged RGCs and that CDKN2A knockdown ameliorates RGC death in mice 15
And many people on tirzepatide fall well below those thresholds, especially during the dose escalation phase when appetite suppression hits hardest
69,70 Further, ambulatory blood-pressure monitoring with patient activity diary can identify presence of postprandial hypotension as well as supine hypertension at night
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