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First, diabetes blunts weight loss by roughly 6 to 7 percentage points versus non-diabetic obesity at the same dose, because long-standing high glucose dampens the metabolic cascade the drug works through. Second, the 10-to-15 mg step keeps adding weight loss in every band

Hercberg, P

Its not FDA-approved yet, but researchers have already dubbed retatrutide groundbreaking

The main difference lies in their uses: Wegovy is typically titrated up to 2.4 mg for weight management, while Ozempic is used at lower doses for diabetes