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Tirzepatide for MASH with fibrosis 15 mg produced a large majority disease-resolution rate versus a small placebo rate: Loomba NEJM 2024 (SYNERGY-NASH)

This dual improvement in glucose and lipid homeostasis suggests potential applications in research focusing on insulin sensitivity and fatty liver prevention

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Ultrasound measurements showed statistically significant increases in dermal thickness in the treatment group versus placebo