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[8] [9] Bupropion (Zyban) is licensed in the UK specifically as an aid to smoking cessation, not for depression, and works on dopamine and noradrenaline pathways

They represent a new therapeutic approach able to act directly on the heart or kidneys, independently of insulin sensitivity (Lopaschuk and Verma, 2020

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For researchers studying tirzepatide's dual GLP-1/GIP receptor mechanism, research-grade compounds are available for laboratory use at a fraction of pharmaceutical pricing