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Transdermal estradiol, delivered through patches or gels rather than oral tablets, bypasses the liver entirely, avoiding the first-pass hepatic metabolism that oral estrogen undergoes and that is associated with increased clotting factor production and thrombotic risk
Este gel crea una sensacin de calor en la piel que aumenta de forma inmediata la sensibilidad intensificando las sensaciones
Symptoms include shakiness, sweating, confusion, and irritability, which can be difficult to distinguish from severe sleep deprivation
Diamant M, Van GL, Guerci B, et al
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