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Cost: GP1 medications can be expensive, and not all insurance plans cover them
In clinical trials, people said they felt full longer and their eating was easier to control
Tanphaichitr N
These medications, which include semaglutide (sold as Ozempic and Wegovy) and tirzepatide (sold as Mounjaro and Zepbound), work by mimicking a natural hormone that regulates appetite, slows gastric emptying, and influences how the brain perceives hunger
ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Brotman et al., 2025)
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