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All experimental protocols used were approved and implemented in accordance with ethical committees and conformed to the highest international standards for the humane care of animals in biomedical research
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Blood vessels in AD exhibit structural irregularities, such as twisting and varying diameters, and may develop cerebral amyloid angiopathy (CAA), significantly contributing to BBB disruption, diminished CBF, and cognitive deficits [19, 94, 184,185,186]
Third, pH shifts occur during freezing because buffer components freeze out of solution at different rates, temporarily creating pockets of extreme pH
doi: 10.3390/molecules27092877 466 PrakashMDStojanovskaLFeehanJNurgaliKDonaldELPlebanskiMet al
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