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Individual results will vary based on factors including age, baseline health condition, starting weight, lifestyle factors, consistency of use, genetic factors, current medications, dietary adherence, physical activity levels, and other individual variables

Most of my patients who have lost weight with GLP-1 agonists have had gradual weight loss over months

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A small pilot study conducted in 2006 randomizing individuals with HFrEF between orlistat and placebo, gave early evidence for improvements in functional capacity with weight loss [50]

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