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Mendias stresses that when it comes to unapproved peptides, there's still a lot where we don't understand the safety profile. Whats Behind the Proposed Change OVER THE YEARS , the gray market for experimental peptides has ballooned, driven initially by bodybuilders looking for a competitive edge and then later by biohackers and people with unmet medical needs

Zepbound (tirzepatide) is approved for weight loss, while Ozempic (semaglutide) is approved for type 2 diabetes, though in some cases it may be prescribed off-label for weight loss

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Supplementary material The Supplementary Material for this article can be found online at: References 1 ArmstrongAWBlauveltACallis DuffinKHuangY-HSavageLJGuoLet al