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Intact polyphenols/polysaccharides that escape microbial degradation in the upper gastrointestinal tract directly activate signaling pathways in intestinal epithelial cells and immune cells (233)
OA, the most common form of arthritis, is a degenerative disease caused by an imbalance in matrix metabolism and is characterized by cartilage destruction
Lifestyle-related oxidative stress outcomes have also been reported
Today, however, it is increasingly recognized that these enzymes play only a complementary role
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