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308 Rather than harboring stable resistance mutations, DTP cells adopt a slow-cycling or quasiquiescent phenotype driven by extensive epigenetic remodeling, transcriptional plasticity and metabolic reprogramming, which collectively constitute core maintenance programs that stabilize the DTP state under therapeutic pressure

Subsequently, the monocytes differentiate into macrophages that regulate various healing processes (Huang et al., 2020)

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While it protects healthy cells, it may also potentially shield cancer cells from certain chemotherapy drugs something we take very seriously