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10.1038/s41598-022-09993-1 157
Prediabetes occurs when blood glucose levels are elevated but not yet within the diagnostic range for diabetes
Tirzepatide (weekly injectable) Dosing frequency: Once weekly, same day each week Half-life: approximately 5 days (120 hours) Peak concentration: 8 to 72 hours after injection Recommended timing approach: The shorter half-life compared to semaglutide means the end-of-week trough is more noticeable
Therefore, we suggest that semaglutide can promote the proliferation and osteogenic differentiation of BMSCs in vitro via the Wnt/LRP5/-catenin signalling pathway
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