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It was designed to treat obesity by targeting peripheral receptors, but some researchers believe it might actually exert its effects through CB1 receptors in the central nervous system 15

Donini LM, Busetto L, Bischoff SC, Cederholm T, Ballesteros-Pomar MD, Batsis JA, et al

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Mammalian Preproglucagon and the PGDPs Structure of Mammalian Proglucagon and Tissue-Specific Processing of Proglucagon into the PGDPs

Notably, glutamate plays a key role in the proliferating cells, not only by contributing to amino acid biosynthesis, but also acts as a nitrogen donor for purine and pyrimidine nucleotides biosynthesis (8, 58)