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Important point #2
Missing doses or irregular timing creates fluctuating drug concentrations that reduce appetite suppression and metabolic benefits
Abstract The growth hormone secretagogue receptor (GHSR1a), the target of the ghrelin peptide, is widely distributed throughout the brain, and, while studies have often reported very low or absent levels of central ghrelin, it is now known that GHSR1a, even in the absence of a natural ligand, has physiological roles
doi: 10.1016/j.biomaterials.2010.01.113 128
2019 Jun Alejandro A Nava-Ocampo, Aleksandra Pastrak, Tony Cruz, Gideon Koren
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