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To determine the importance of APTF-1-4 in regulating glp-1 expression, we used RNAi to individually knock down their expression in wild-type animals for 16 h from the L4 larval stage and measured GLP-1::V5 levels in the adult germline (Fig

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Sin embargo, estos estudios presentan limitaciones metodolgicas significativas, incluyendo tamaos de muestra pequeos, falta de estandarizacin de dosis, alta heterogeneidad entre estudios y variabilidad en las poblaciones estudiadas

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