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When GLP-1 binds to receptors in these areas, it activates anorexigenic (appetite-suppressing) neurons whilst inhibiting orexigenic (appetite-stimulating) pathways, contributing to reduced food intake and increased satiety
Incretin hormones, along with the chemically similar GLP-1 receptor agonists, slow gut motility and, therefore, slow the emptying of the gastrointestinal tract
Bain, S.L
Nature Communications 8:422
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