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However, the study affirms that EGCG is generally well tolerated in humans and supports the idea that EGCG therapy acting on the -synuclein oligomer formation may be an effective target for the treatment of neurodegenerative diseases (225)
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Biomacromolecules 16 , 962972 (2015)
These changes in protein expression bring about the fragmentation of mitochondria and their accumulation around the nucleus, which might deprive dendrites and axons of mitochondria [318]
In the brain, thiamine is phosphorylated at the cellular level to form its active derivative, thiamine pyrophosphate (TPP) (6, 11, 33)
These proteins belong to the NLRC subfamily, characterized by their CARD domains, and were the first mammalian NLRs to be characterized
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