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However, more investigations are warranted to expand their applications to meet the evolving dermatological challenges

Mukherjee et al., 2020)

Injectable protocols are not FDA-approved for cosmetic use, and long-term data from controlled trials is limited

13% of the participants treated with the combined compound ended up discontinuing the trial, while 10% of the participants treated with semaglutide discontinued, however, none of the participants treated with cagrilintide discontinued their treatment plan indicating that cagrilintide was the most well tolerated by the study participants [2]

Surprisingly, this result was consistent with the results of GPX1 KO mice compared to WT mice