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Hypoglycaemia is uncommon with GLP-1 monotherapy but can occur when combined with insulin or sulfonylureas
Its worth noting that maintaining significant weight loss results requires understanding the factors that may affect the medications efficacy and compromise ones health, such as semaglutide and alcohol, and semaglutide and breastfeeding
As of late 2025, the U.S
Trial results reflect study populations under clinical supervision alongside lifestyle intervention
These limitations reduce confidence in the pooled estimates
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