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The UKPDS study demonstrated reduced cardiovascular mortality in overweight patients treated with Metformin compared to other diabetes treatments
Rosenstock et al., Lancet, 2023
The SELECT trial (2023) further demonstrated semaglutide 2.4 mg significantly reduced MACE risk in non-diabetic adults with obesity and established CV disease, supporting Wegovy's CV indication
Some apparent weight loss from weight loss pills is water weight, which returns quickly if you stop taking them
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