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A single exposure (A) causes a small decrease (less than 3% of normal), in both blood and cytosolic GSH and Cys concentrations, with levels returning to above 99% of normal for all species within the simulated time-span
The former showed an improvement in the enteric nerve system [31] and also lowered the systemic levels of proinflammatory cytokines, which may lead to the prevention of future peripheral neuropathy in early stages of diabetes mellitus, although more evidence is required [32]
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subsequent discoveries have revealed the epigenetic functions of lactate through histone lysine lactylation (Kla), a post-translational modification analogous to acetylation and succinylation (9,10)
doi: 10.1007/s10719-009-9239-8 299 AbdulkhalekSAmithSRFranchukSLJayanthPGuoMFinlayTet al
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