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How well do you tolerate gastrointestinal side effects
Its very alkaline (you know the opposite of being very acidic): a 1% solution has a pH of around 10
Tirzepatide accelerated it
In atherosclerosis, GPER promotes smooth muscle cell proliferation and migration via the PI3K/AKT pathway [197, 198] and reduces oxidative stress by downregulating Nox1 expression, thereby decreasing reactive oxygen species production [199]
So whatever you're experiencing there is very nicely supported by the data
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