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It is for this reason that neurodegenerative diseases such as Parkinsons, Alzheimers, multiple sclerosis and amyotrophic lateral sclerosis (ALS) all share some level of free radical accumulation and destruction of neurophysiological function through lipid peroxidation
In the general population, 20% have genetic defects for increased coagulation
Exclude pregnant or breastfeeding women, anyone under 18, and people with liver or kidney disease, bipolar or seizure disorders, or B-vitamin sensitivity, since each carries real physiological risk outside a controlled setting
DPP-4 inhibitors can be administered in patients with impaired kidney function due to the good safety and tolerability
