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The -aminoisobutyric acid (Aib) residue at position 1 confers resistance to N-terminal peptidase cleavage
Most side effects diminish within the first month or two of treatment
Acta 126 LyttleM
Gastrointestinal models report protection against NSAID-induced and ethanol-induced mucosal injury
Some side effects that are more serious than others are: Chills Fever Fatigue Tachycardia (Heart rate that is too fast) Diarrhea Fever with lowered white blood cell count Swelling in the body (most often in the legs and feet) Low blood pressure (hypotension) with a skin rash Alopecia (hair loss that is temporary or permanent) Infection Low levels of oxygen in the body (hypoxia) Shortness of breath After finishing lifileucel treatment, it is important to stay within two hours travel time of the treatment location
