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Oral daily orforglipron (Foundayo): The newest GLP-1 on the market launched with a price of $149 per month for starter doses and up to $349 per month for the maximum dose when purchased without insurance

This group had nearly 5% fewer knee replacements over eight years

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Combining GLP-1 therapy with regular physical activity offers additional benefits, including preservation of lean muscle mass, improved cardiovascular health, and enhanced long-term weight maintenance