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Initially GLP-1 was described as an incretin hormone that stimulates glucose-dependent insulin secretion, increases insulin biosynthesis, improves beta-cell function and acts as a glucagonostatic regulator (145148)
Ethics 47 (8), 531538
Orforglipron, however, avoids this problem entirely
These medications mimic a naturally occurring hormone, GLP-1, which regulates blood sugar and appetite
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