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Recently, the pharmacotherapy of MASLD mainly focuses on three parts of mechanisms: anti-inflammatory (ASK1 inhibitors), anti-diabetic (GCGR agonists, PPAR agonists), and prevention of lipotoxicity (FXR agonists, FGF21 analogues) (Wei et al., 2024)
A decrease in the cellular antioxidant concentration is associated with the generation of an excess of ROS (Chae et al., 2000
That presents serious safety concerns of its own
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
Clinical Manifestations If an individual is exposed to or engages in the lifestyle predispositions mentioned above, clinical manifestations (highlighted in the white boxes in the above graphic) may start to unfold
