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Diabetes Obes Metabolism
the dose is then increased to 7 mg once daily for glycemic control [24, 70]
Methods Animal experiments The humanized Townes SCD transgenic (B6;129- Hba tm1(HBA)Tow Hbb tm2(HBG1,HBB*)Tow / Hbb tm3(HBG1,HBB)Tow /J) mouse 65 was obtained from Jackson Laboratories ( as breeders
GLP-1RA exerts its glucose lowering effect by stimulating GLP-1 receptors, which not only has significant glucose-lowering efficacy, but also has the advantage of low incidence of hypoglycemia
It upregulates genes for collagen types I and III, the glycosaminoglycans decorin and dermatan sulfate, and vascular endothelial growth factor (VEGF) [3]
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