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used alloxan-induced diabetic rats to study the hypoglycemic effect of durian rind extract

Clinical response correlates strongly with early intervention

This product is sold for laboratory research use only and is not intended to diagnose, treat, cure, or prevent any disease

Like other incretin-based therapies, it requires a stepwise titration protocol to balance effectiveness with safety, particularly gastrointestinal side effects that tend to appear at higher doses

But beneath this simple equation lies a complex web of hormonal and neurological signalsmost notably through the gut-brain axis, where hormones produced in the gastrointestinal tract signal the brain to regulate food intake, energy expenditure and glucose homeostasis