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[7] [14] Participants receiving higher doses of retatrutide (particularly 8 mg and 12 mg weekly) experienced mean increases in heart rate of approximately 5 to 7 beats per minute (bpm) above baseline, based on data reported in the 2023 NEJM Phase 2 publications

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Current Results with Semaglutide : If youre achieving your weight or blood sugar goals, consider whether switching is necessary

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Glucagon receptor activation does not directly suppress appetite in the way GLP-1 does