Temporarily focus on these easy-to-digest options: Starches: White rice, rice cakes, saltine crackers, white toast, plain mashed potatoes (avoiding heavy butter/cream) Proteins: Lean sources like baked or grilled chicken breast (skinless), baked fish, or eggs Fruits: Bananas, unsweetened applesauce, and canned peaches Vegetables: Cooked carrots, soft squash, or peeled, seedless vegetables You should also temporarily avoid two major categories of gut irritants: Spicy foods: Chili peppers and strong spices can irritate the stomach lining Simple sugars/sweeteners: Sugary drinks and products containing artificial sweeteners or sugar alcohols (like sorbitol or xylitol) can draw water into the colon, making diarrhea worse Eating small, frequent, low-fat meals Eating a large meal sends a strong signal to your digestive system, which can trigger the motility changes that cause diarrhea
You can inject in a fasted or fed state without changing absorption
In December 2025, federal courts consolidated NAION lawsuits into an MDL proceeding in the Eastern District of Pennsylvania
Structure Therapeutics has already disclosed an oral small-molecule amylin program (ACCG-2671, ACCG-3535) intended for fixed-dose combination with GLP-1RAs, and is working on small-molecule agonists at GIP, glucagon and apelin receptors
Outsourcing facilities (Section 503B) will be permitted to compound tirzepatide until March 19, 2025