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health insurance landscape creates both the opportunity and the constraint: commercial insurance covering GLP-1 for diabetes generates large, well-reimbursed prescription volumes, but coverage for obesity indications varies widely, with Medicare explicitly prohibited from covering weight loss drugs until the Treat and Reduce Obesity Act passes a legislative gap that excludes tens of millions of Medicare beneficiaries from covered GLP-1 obesity access

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Thus, DPDP increased the activities of antioxidant enzymes, including GPX, enhancing the efficiency of ROS elimination by the host, and consequently inhibiting disease progression (Hassan et al., 2013) ( Supplementary Table S3 )